Prof.
University of Bern
Author in the following contributions
- Analysis of androgen modulation by natural products
- Structural and Enzymatic Profiling of CYP17A1 Mutations Defines the Molecular Basis of Partial Enzyme Deficiencies
- Ligand Access and Egress Pathways in Human Cytochrome P450 CYP17A1
- Seviterenol Demonstrates Selective CYP17A1 Lyase Inhibition with Reduced Off-Target Activity and Minimal Ferroptotic Effects in Prostate Cancer Models
- Rewiring the Redox Hub by Computational Redesign and Functional Profiling of Human P450 Oxidoreductase
- Integrated Mapping Resolves Pathogenicity of Eleven CYP21A2 Variants in Congenital Adrenal Hyperplasia.
- P450 Oxidoreductase Dysregulation: A Negative Prognostic Marker and Somatic Target in High-Mortality Cancers